General Information

Name: Rabeprazole Gastro-Resistant Tablet I.P.

Drug Class: Proton Pump Inhibitor (PPI)

Form: Gastro-resistant tablet (delayed-release)

1-Reduces Stomach Acid Production

Gastroesophageal reflux disease (GERD)

Peptic ulcers

Zollinger-Ellison syndrome

Acid reflux

Helicobacter pylori infection (in combination with antibiotics)

2-Promotes Healing of Ulcers

Creates a favorable environment in the stomach and intestines for healing. 3-Prevents Ulcer Recurrence

Particularly useful for long-term management of chronic conditions like GERD.

4-Usually Well-Tolerated

Fewer short-term side effects compared to other acid-suppressing drugs like H2 blockers

5-Convenient Dosing

Typically taken once daily, which improves compliance.

Common (but usually mild):

Headache

Nausea

Diarrhea or constipation

Abdominal pain or flatulence

Dizziness

Less Common but Serious (especially with long-term use):

Vitamin B12 Deficiency

Acid = ↓ B12 absorption over time

Magnesium Deficiency(Hypomagnesemia)

Can lead to muscle cramps, irregular heartbeat

Increased Risk of Fractures

Especially in elderly with long-term use (due to decreased calcium absorption)

Kidney Problems (e.g., interstitial nephritis)

Rare but possible; watch for unexplained fatigue or swelling

Increased Risk of Infections e.g., Clostridium difficile in the intestines, pneumonia

Lupus-like symptoms

Rare autoimmune response (rash, joint pain)